Research

Create new classes of immunotherapy to solve ageing-related diseases

Publications:

Yuba E, Budina E, Katsumata K, Ishihara A, Mansurov A, Alpar AT, Watkins EA, Hosseinchi P, Reda JW, Lauterbach AL, Nguyen M, Solanki A, Kageyama T, Swartz MA, Ishihara J, Hubbell JA. 2020

Enhanced lymph node trafficking of engineered IL-10 suppresses rheumatoid arthritis in murine models.

Arthritis and Rheumatology

Ishihara A, Ishihara J, Watkins EA, Tremain AC, Nguyen M, Solanki A, Katsumata K, Mansurov A, Budina E, Alpar AT, Hosseinchi P, Maillat L, Reda JW, Kageyama T, Swartz MA, Yuba E, Hubbell JA, 2020, Prolonged residence of an albumin–IL-4 fusion protein in secondary lymphoid organs ameliorates experimental autoimmune encephalomyelitis, Nature Biomedical Engineering, ISSN: 2157-846X


Katsumata K, Ishihara J, Fukunaga K, Ishihara A, Yuba E, Budina E, Hubbell JA, 2019, Conferring extracellular matrix affinity enhances local therapeutic efficacy of anti-TNF-α antibody in a murine model of rheumatoid arthritis, Arthritis Research and Therapy, Vol: 21, Pages: 1-10, ISSN: 1478-6354


Katsumata K, Ishihara J, Mansurov A, Ishihara A, Raczy MM, Yuba E, Hubbell JA, 2019, Targeting inflammatory sites through collagen affinity enhances the therapeutic efficacy of anti-inflammatory antibodies, Science Advances, Vol: 5, Pages: 1-9, ISSN: 2375-2548